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爱必信产品描述：

中文名称：离子载体

英文名称：ionophore A23187

CAS：52665-69-7

纯度：≥97%

别名：Calimycin; Antibiotic A 23187

来源：Streptomyces chartreusis

产品描述：

A23187 is an ionophore, highly selective for Ca²⁺, that allows for divalent cations to move across the membranes which are usually impermeable to them. The compound was originally isolated from Streptomyces chartreusensis for use as an antibiotic but has been shown to have weak in vitro antimicrobial activity against fungi and gram positive bacteria. Because of its ability to increase intracellular calcium levels of intact cells, it is used in studies of intracellular Ca²⁺ mediated events. A23187 has been observed to induce cell activation, differentiation or proliferation. In vitro experimentation has shown A23187 to boost ROS generation and platelet fragmentation.

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