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产品描述:

产品名称:Human NKp30 / NCR3 / CD337 Protein

背景说明: NKp30, along with NKp44 and NKp46, constitute a group of receptors termed “Natural Cytotoxicity Receptors” . These receptors play a major role in triggering NK-mediated killing of most tumor cells lines.NKp30 stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG which promote DC maturation.

别名: CD337 antigen; CD337; Activating natural killer receptor p30; CD337activating NK-A1 receptor; LY117,1C7NK-p30; lymphocyte antigen 117; natural cytotoxicity triggering receptor 3; Natural killer cell p30-related protein; NCR3; NKp30; NKp30MALS

Accession: AAH52582

序列: Leu19-Thr138

种属: Human

来源: Human NKp30 Protein is expressed from mammalian with His Tag and Avi Tag at the C-terminal.;It contains Leu19-Thr138.

分子量: The protein has a predicted MW of 20 KDa. Due to glycosylation, the protein migrates to 26-45KDa based on Bis-Tris PAGE result.

纯度: > 95% as determined by SDS-PAGE;> 95% as determined by HPLC

内毒素水平: Less than 1 EU per μg by the LAL method.

形态: Lyophilized from 0.22um filtered solution in PBS (pH 7.4).Normally 5 % trehalose is added as protectant before lyophilization.

储存/保存方法: The product should be stored at -70℃ or -20℃.

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