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产品描述:

产品名称:Human LILRB4 / CD85k / ILT3 Protein

别名: CD85 antigen-like family member K; CD85k antigen; CD85k; HM18; ILT3; ILT-3; ILT3CD85K; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains); LILRB4; LIR5; LIR5LILRB5; LIR-5subfamily B, member 4; member 4

背景说明: LILRB4,also known as CD85k and LIR-5, ILT3,  is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles.

序列: Gln 22 - Arg256

Accession: AAH26309

种属: Human

来源: Human LILRB4 Protein is expressed from mammalian with hFc Tag at the C-terminal.;It contains Gln 22 - Arg256.

分子量: The protein has a predicted MW of 52.6 KDa. Due to glycosylation, the protein migrates to 64-66KDa based on Bis-Tris PAGE result.

纯度: > 95% as determined by SDS-PAGE;> 95% as determined by HPLC

内毒素水平: Less than 1 EU per μg by the LAL method.

形态: Lyophilized from 0.22um filtered solution in PBS (pH 7.4).Normally 5 % trehalose is added as protectant before lyophilization.

储存/保存方法: The product should be stored at -70℃ or -20℃.

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