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产品描述:

产品名称:Human IL-34 Protein

背景说明: Interleukin 34 (IL-34; also known as uncharacterized protein C16orf77) is secreted as a homodimer consisting of 39 kDa monomers. It belongs to no known cytokine family.Interleukin 34 is cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.

别名: C16orf77; IL34; IL-34; interleukin 34

Accession: Q6ZMJ4

序列: [Native SP]Asn21-Pro242<His-avi>

种属: Human

来源: Human IL-34 Protein is expressed from mammalian with His and Avi Tag at the C-terminal. ;It contains Asn21-Pro242.

分子量: The protein has a predicted MW of 28.1KDa.

纯度: NULL

内毒素水平: Less than 1 EU per μg by the LAL method.

形态: Lyophilized from 0.22um filtered solution in PBS (pH 7.4).Normally 5 % trehalose is added as protectant before lyophilization.

储存/保存方法: The product should be stored at -70℃ or -20℃.

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