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产品描述:

产品名称:Human FcRn Heterodimer Protein

背景说明: The neonatal Fc receptor (FCRN) is an approximately 45 kDa transmembrane glycoprotein with structural homology to MHC class I proteins. It is widely expressed in endothelial and epithelial cells and plays an important role in IgG homeostasis and antigen presentation by dendritic cells.FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51, and p14 , and forms an MHC class I-like heterodimer.

别名: FcRn alpha chain;alpha-chain; Fc fragment of IgG, receptor, transporter, alpha; FCGRT; FCRN; FCRNimmunoglobulin receptor, intestinal, heavy chain; IgG Fc fragment receptor transporter alpha chain; IgG receptor FcRn large subunit p51; major histocompatibility complex class I-like Fc receptor; Neonatal Fc receptor; neonatal Fc-receptor for Ig

Accession: P55899-1&P61769-1

序列: [Rituximab SP];B2M (21-119); 4GS-linker;FcRn (24-297); GS-linker;<8His tag><Avi tag>

种属: Human

来源: Human FcRn is expressed from mammalian with a His tag and Avi Tag at the C-terminal.;It contains Ile 21 - Met 119(B2M)& Ala 24 - Ser 297 (FCGRT) .

分子量: The protein has a predicted MW of 46.5 kDa same as Bis-Tris PAGE result.

纯度: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

内毒素水平: Less than 1 EU per μg by the LAL method.

形态: Lyophilized from 0.22um filtered solution in PBS (pH 7.4).Normally 5 % trehalose is added as protectant before lyophilization.

储存/保存方法: The product should be stored at -70℃ or -20℃.

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