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产品描述:

产品名称:Human IL-17C Protein

背景说明: Interleukin?17C (IL?17C) is a 15?20 kDa glycosylated cytokine that plays an important role in mucosal immunity and chronic inflammation. The six IL?17 cytokines (IL?17A?F) are encoded by separate genes but adopt a conserved cystine knot fold. IL?17C is Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G.

别名: CX2; Cytokine CX2; IL17C; IL-17C; IL-17CMGC126884; interleukin 17C; interleukin-17C; MGC138401

序列: His19-Val197.

Accession: Q9P0M4

种属: Human

来源: Recombinant Human IL-17C Protein is expressed from mammalian with His and Avi Tag at the C-terminal.;It contains His19-Val197.

分子量: The protein has a predicted MW of 22.6 kDa. Due to glycosylation, the protein migrates to 25KDa based on Bis-Tris PAGE result.

纯度: > 95% as determined by Bis-Tris PAGE;

内毒素水平: Less than 1 EU per μg by the LAL method.

形态: Lyophilized from 0.22um filtered solution in PBS (pH 7.4).Normally 5 % trehalose is added as protectant before lyophilization.

储存/保存方法: The product should be stored at -70℃ or -20℃.

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