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产品描述:

产品名称:Human Siglec-8 Protein

背景说明: Siglec-8, also known as SAF, is an approximately 75 kDa transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-8 consists of a 347 amino acid (aa) extracellular domain (ECD) with three Ig-like domains.Putative adhesion molecule that mediates sialic-acid dependent binding to red blood cells. Preferentially binds to alpha-2,3-linked sialic acid. Also binds to alpha-2,6-linked sialic acid.

别名: CD329 antigen; CDw329; MGC59785; SAF2; SAF2SAF-2; sialic acid binding Ig-like lectin 8; Sialoadhesin family member 2; Siglec8; Siglec-8; SIGLEC8L; SIGLEC8Lsialic acid-binding Ig-like lectin 8

序列: [Native SP] Met17-Ala363 <His-avi>

Accession: Q9NYZ4

种属: Human

来源: Recombinant Human siglec 8 Protein is expressed from mammalian with a His Tag and Avi Tag at the C-terminal.;It contains Met17-Ala363.

分子量: The protein has a predicted MW of 40.7 kDa.Due to glycosylation, the protein migrates to 50-60KDa based onBis-Tris PAGE result.

纯度: > 95% as determined by Tris-Bis -PAGE;> 95% as determined by HPLC

内毒素水平: Less than 1 EU per μg by the LAL method.

形态: Lyophilized from 0.22um filtered solution in PBS (pH 7.4).Normally 5 % trehalose is added as protectant before lyophilization.

储存/保存方法: The product should be stored at -70℃ or -20℃.

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