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产品描述:

产品名称:Human HLA-A*0201 WT-1 (RMFPNAPYL) complex Protein (tetramer)

背景说明: The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, endometrioid, clear cell, and mucinous carcinomas of the peritoneum, fallopian tube, ovary, and endometrium.The Human HLA-A*0201 WT-1 (RMFPNAPYL) complex Protein is a complex of HLA-A*0201 of  the MHC Class I, B2M and RMFPNAPYL peptide of  the WT-1.

别名: MHC, WT1, RMF, Wilms tumor protein

Accession: P01892

序列: Gly 25 - Thr 305 (HLA-A*0201),Ile21-Met119 (B2M) and RMFPNAPYL peptide design

种属: Human

来源: Human HLA-A*0201 WT-1 (RMFPNAPYL) complex protein is expressed from mammalian with a polyHisand avi tag at the C-terminal,tetramer is assembled by biotinylated monomer and streptavidin.;It contains Gly 25 - Thr 305 (HLA-A*0201),Ile21-Met119 (B2M) and RMF

分子量: Human HLA-A*0201 WT-1 (RMFPNAPYL) complex Protein has a calculated MW of 50.5kDa. The protein(tetramer) migrates as 240-260 kDa under Non reducing (N) condition (Bis-Tris PAGE) .

纯度: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

内毒素水平: Less than 1 EU per μg by the LAL method.

形态: Lyophilized from 0.22um filtered solution in PBS (pH 7.4).Normally 5 % trehalose is added as protectant before lyophilization.

储存/保存方法: The product should be stored at -70℃ or -20℃.

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