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产品描述:

产品名称:Biotinylated Human B7-H3 (4Ig) / B7-H3b Protein

背景说明: B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig?B7?H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma ) production, and cytotoxic T cells induction.

别名: B7H3; B7-H3; CD276 antigen; CD276 molecule; CD276; B7H34Ig-B7-H3; B7-H3B7 homolog 3; Costimulatory molecule

序列: Gly27 - Thr461

Accession: Q5ZPR3-1

种属: Human

来源: Biotinylated Recombinant Human B7-H3b Protein is expressed from Expi293 with a His and Avi Tag at the C-terminal.;It contains Gly27 - Thr461.

分子量: The protein has a predicted MW of 49.5 kDa.Due to glycosylation, the protein migrates to 70-80 KDa based onBis-Tris PAGE result.

纯度: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

内毒素水平: Less than 1 EU per μg by the LAL method.

形态: Lyophilized from 0.22um filtered solution in PBS (pH 7.4).Normally 5 % trehalose is added as protectant before lyophilization.

储存/保存方法: The product should be stored at -70℃ or -20℃.

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