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产品描述:

产品名称:Biotinylated Human siglec-10 Protein

别名: siglec 10; siglec-10; siglec10; Sialic acid-binding Ig-like lectin 10; Siglec-like protein 2; SLG

背景说明: Siglec-10 is a ligand for CD52, the target of the therapeutic monoclonal antibody Alemtuzumab. It is also reported to bind to Vascular adhesion protein 1 (VAP-1) and to the co-stimulatory molecule CD24 also known as HSA (Heat-stable antigen).Siglecs (sialic acid binding Ig-like lectins) are I-type lectins that belong to the immunoglobulin superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by a varying number of Ig-like C2-type domains. Siglecs 5-11 constitute the CD33/Siglec-3 related group, and are differentially expressed in the hematopoietic system.

序列: Met17-Thr546

Accession: Q96LC7

种属: Human

来源: Biotinylated Recombinant Human siglec 10 Protein is expressed from mammalian with Fc and AviTag at the C-terminal.;It contains Met17-Thr546.

分子量: The protein has a predicted MW of 85.8KDa. Due to glycosylation, the protein migrates to 95-110KDa based on Bis-Tris PAGE result.

纯度: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

内毒素水平: Less than 1 EU per μg by the LAL method.

形态: Lyophilized from 0.22um filtered solution in PBS (pH 7.4).Normally 5 % trehalose is added as protectant before lyophilization.

储存/保存方法: The product should be stored at -70℃ or -20℃.

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