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产品描述:

产品名称:Biotinylated Human IL-17A&IL-17F heterodimer Protein

背景说明: Interleukin?17A (IL?17A), also known as CTLA?8, is a 15?20 kDa glycosylated cytokine that plays an important role in anti?microbial and chronic inflammation. The six IL?17 cytokines (IL?17A?F) are encoded by separate genes but adopt a conserved cystine knot fold .IL-17A is a ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC . Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines.

别名: IL-17A,Interleukin-17A,CTLA-8,IL-17,IL-17F,IL24,ML-1,Interleukin-17F

Accession: Q16552-1&Q96PD4

序列: Gly 24 - Ala 155 (IL-17A) & Arg31-Gln163

种属: Human

来源: Biotinylated Recombinant human IL17A&F Protein is expressed from mammalian with a His Tagand Avi Tag at the C-terminal.;It contains Gly 24 - Ala 155 (IL-17A) & Arg31-Gln163 .

分子量: The protein has a predicted MW of 15.1 kDa (Q16552-1) &17.5 kDa (Q96PD4).Due toglycosylation, the protein migrates to 16KDa&27KDa based on Bis-Tris PAGE result.

纯度: > 95% as determined by Tris-Bis PAGE

内毒素水平: Less than 1 EU per μg by the LAL method.

形态: Lyophilized from 0.22um filtered solution in PBS (pH 7.4).Normally 5 % trehalose is added as protectant before lyophilization.

储存/保存方法: The product should be stored at -70℃ or -20℃.

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