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产品描述:

产品名称:Biotinylated Human CD3 epsilon & CD3 gamma Heterodimer Protein

背景说明: T-cell surface glycoprotein CD3 epsilon & CD3 gamma chain, also known as CD3E & CD3G , are single-pass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain.

别名: CD3;CD3D;CD3-DELTA;T3D;CD3G

序列: Asp 23 - Asp 126 (CD3E) & Gln 23 - Ser 116 (CD3G)

Accession: P07766 & P09693

种属: Human

来源: Biotinylated Human CD3 epsilon & CD3 gamma Heterodimer Protein is expressed from mammalianwith a Fc and Avi Tag at the C-terminal.;It contains Asp 23 - Asp 126 (CD3E) & Gln 23 - Ser 116 (CD3G).

分子量: The protein has a calculated MW of 40 kDa (CD3E) and 36.5 kDa (CD3G). As a result ofglycosylation, the protein migrates to 75-90 kDa based on Bis-Tris PAGE result.

纯度: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

内毒素水平: Less than 1 EU per μg by the LAL method.

形态: Lyophilized from 0.22um filtered solution in PBS (pH 7.4).Normally 5 % trehalose is added as protectant before lyophilization.

储存/保存方法: The product should be stored at -70℃ or -20℃.

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