公告提醒:爱必信所有产品和服务仅用于科学研究,不用于及其他用途提供产品和服务(也不为任何个人提供产品和服务)!

产品描述:

产品名称:Human FGFR4 Protein

背景说明: Fibroblast growth factor receptor 4 (FGF R4), also known as CD334, is a 110 kDa glycosylated transmembrane receptor tyrosine kinase.Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism and phosphate homeostasis. Required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19.

别名: CD334 antigen; CD334; EC 2.7.10; EC 2.7.10.1; FGF R4; FGFR4; FGFR-4; fibroblast growth factor receptor 4; JTK2hydroxyaryl-protein kinase; MGC20292; protein-tyrosine kinase; TKF; tyrosine kinase related to fibroblast growth factor receptor; tyrosylprotein kinase

Accession: P22455

序列: Leu22-Asp369

种属: Human

来源: Recombinant Human FGFR4 Protein is expressed from mammalian with a His tag and Avi Tag atthe C-terminal.;It contains Leu22-Asp369.

分子量: The protein has a predicted MW of 41.4 kDa.Due to glycosylation, the protein migrates to 60-75KDa based on Bis-Tris PAGE result.

纯度: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

内毒素水平: Less than 1 EU per μg by the LAL method.

形态: Lyophilized from 0.22um filtered solution in 20mM PB,150mM NaCl, pH 7.4.Normally 5 % trehalose is added as protectant before lyophilization.

储存/保存方法: The product should be stored at -70℃ or -20℃.

产品信息订购:

产品更多信息请进入爱必信网站咨询