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产品描述:

产品名称:Human FOLR1 Protein

背景说明: Folate Receptor 1 (FOLR1), also known as Folate Receptor alpha and Folate Binding Protein (FBP), is a 37 - 42 kDa protein that mediates the cellular uptake of folic acid and reduced folates. Dietary folates are required for many key metabolic processes including nucleotide and methionine synthesis, the interconversion of glycine and serine, and histidine breakdown. FOLR1 binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH.

别名: FOLR; FOLR1; FR-alpha;Adult folate-binding protein; FBP; folate binding protein; folate receptor 1 (adult); Folate receptor 1; folate receptor alpha; Folate receptor, adult; Folbp1; KB cells FBP; MOv18; Ovarian tumor-associated antigen MOv18

Accession: P15328

序列: Arg25-Met233

种属: Human

来源: Human FOLR1 Protein is expressed from mammalian with a poly-His and Avi tag at the C-terminal.;It contains Arg25-Met233 .

分子量: The Protein has a calculated MW of 27.5kDa. As a result of glycosylation, the protein migrates to38-45 kDa based on Bis-Tris PAGE.

纯度: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

内毒素水平: Less than 1 EU per μg by the LAL method.

形态: Lyophilized from 0.22um filtered solution in PBS (pH 7.4).Normally 5 % trehalose is added as protectant before lyophilization.

储存/保存方法: The product should be stored at -70℃ or -20℃.

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