公告提醒:爱必信所有产品和服务仅用于科学研究,不用于及其他用途提供产品和服务(也不为任何个人提供产品和服务)!

产品描述:

产品名称:Human FGFR3 beta (IIIc) Protein

别名: CD333; CEK; EC 2.7.10; FGF R3; FGFR3; fibroblast growth factor receptor 3; HSFGFR3EX; JTK4; JTK4thanatophoric dwarfism

背景说明: Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid?box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain.FGFR3 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis. Plays an essential role in the regulation of chondrocyte differentiation, proliferation and apoptosis, and is required for normal skeleton development. Regulates both osteogenesis and postnatal bone mineralization by osteoblasts.

序列: Asp127-Gly377<His-avi>

Accession: P22607

种属: Human

来源: Recombinant Human FGFR3 beta (IIIc) Protein is expressed from mammalian with His Tag and Avi Tag at the C-terminal.;It contains Asp127-Gly377.

分子量: The protein has a predicted MW of 30.1 KDa. Due to glycosylation, the protein migrates to 50-60KDa based on Bis-Tris PAGE result.

纯度: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

内毒素水平: Less than 1 EU per μg by the LAL method.

形态: Lyophilized from 0.22um filtered solution in PBS (pH 7.4).Normally 5 % trehalose is added as protectant before lyophilization.

储存/保存方法: The product should be stored at -70℃ or -20℃.

产品信息订购:

产品更多信息请进入爱必信网站咨询