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产品描述:

产品名称:Cynomolgus CD40 / TNFRSF5 Protein

别名: CD40; CD40L receptor;  TNFRSF5;B cell surface antigen CD40; B-cell surface antigen CD40; Bp50B cell-associated molecule; CD40 antigen; CD40 molecule, TNF receptor superfamily member 5; CD40 type II isoform;CDw40; MGC9013; nerve growth factor receptor-related B-lymphocyte activation molecule; p50; TNFRSF5CD40 antigen (TNF receptor superfamily member 5); tumor necrosis factor receptor superfamily member 5; tumor necrosis factor receptor superfamily, member 5

背景说明: CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects.CD40 molecule is a potential target for cancer immunotherapy. There are number of completed and ongoing clinical trials where agonistic anti-CD40 monoclonal antibodies are employed to activate an anti-tumor T cell response via activation of dendritic cells.

序列: Glu 21 - Arg 193

Accession: G7PG38

种属: Cynomolgus

来源: Recombinant Cynomolgus CD40 Protein is expressed from HEK293 with a His tag at the C-terminal.;It contains Glu 21 - Arg 193 .

分子量: The protein has a predicted MW of 20.3 kDa. Due to glycosylation, the protein migrates to 30-40KDbased on Bis-Tris PAGE result.

纯度: > 95% as determined by SDS-PAGE;> 95% as determined by HPLC

内毒素水平: Less than 1 EU per μg by the LAL method.

形态: Lyophilized from 0.22um filtered solution in PBS (pH 7.4).Normally 5 % trehalose is added as protectant before lyophilization.

储存/保存方法: The product should be stored at -70℃ or -20℃.

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