公告提醒:爱必信所有产品和服务仅用于科学研究,不用于及其他用途提供产品和服务(也不为任何个人提供产品和服务)!

产品描述:

产品名称:Biotinylated Human FGFR1 alpha (IIIc) Protein

别名: FGF R1a; FGFR1 alpha

背景说明: Fibroblast growth factors (FGFs) comprise a family of at least eighteen structurally related proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differentiation, angiogenesis, wound healing and tumorgenesis. The biological activities of the FGFs are mediated by a family of type I transmembrane tyrosine kinases which undergo dimerization and autophosphorylation after ligand binding.FGFR1 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and correct axial organization during embryonic development, normal skeletogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system.

序列: Arg22-Glu374

Accession: P11362

种属: Human

来源: Biotinylated Human FGFR1 alpha (IIIc) Protein is expressed from mammalian with His Tag and Avi Tag at the C-terminal.;It contains Arg22-Glu374.

分子量: The protein has a predicted MW of 42 KDa. Due to glycosylation, the protein migrates to 68-80 KDa based on Bis-TrisPAGE result.

纯度: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

内毒素水平: Less than 1 EU per μg by the LAL method.

形态: Lyophilized from 0.22um filtered solution in PBS (pH 7.4).Normally 5 % trehalose is added as protectant before lyophilization.

储存/保存方法: The product should be stored at -70℃ or -20℃.

产品信息订购:

产品更多信息请进入爱必信网站咨询