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产品描述:

产品名称:Human LILRA3 / CD85e Protein

背景说明: Human LILRA3, also known as Leukocyte Ig-like receptor 4 (LIR-4), CD85 antigen-like family member E, Immunogobulin-like transcript 6 (ILT-6) and monocyte inhibitory receptor HM43/HM31,  is a 70 kD Ig superfamily member that belongs to the leukocyte receptor complex/cluster. Mature LILRA3 is 416 amino acids (aa) in length and contains four C2-type Ig-like domains . Unlike other LILR family members, LILRA3 is actively secreted.LILRA3 acts as soluble receptor for class I MHC antigens. LILRA3 binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes.

别名: CD85 antigen-like family member E; CD85e antigen; CD85e; HM31; HM43; ILT6; ILT-6; ILT6CD85e; Immunoglobulin-like transcript 6; leucocyte immunoglobulin-like receptor; Leukocyte immunoglobulin-like receptor 4; leukocyte immunoglobulin-like receptor A3; leukocyte immunoglobulin-like receptor subfamily A member 3; leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member3; LILRA3; LIR4; LIR4CD85E; LIR-4HM43e3; Monocyte inhibitory receptor HM43/HM31

序列: Gly24-Glu439

Accession: Q8N6C8

种属: Human

来源: Human LILRA3 Protein is expressed from mammalian with His and Avi Tag at the C-terminal.;It contains Gly24-Glu439.

分子量: The protein has a predicted MW of 47.9 kDa .Due to glycosylation, the protein migrates to 68-72KDa based on Bis-Tris PAGE result.

纯度: > 95% as determined by SDS-PAGE;> 90% as determined by HPLC

内毒素水平: Less than 1 EU per μg by the LAL method.

形态: Lyophilized from 0.22um filtered solution in 20mM PB, 150mM NaCl (pH 7.4).

储存/保存方法: The product should be stored at -70℃ or -20℃.

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