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产品描述:

产品名称:SR 11302

别名: (E,E,Z,E)-3-Methyl-7-(4-methylphenyl)-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid

CAS号: 160162-42-5

描述: SR 11302 is an inhibitor of activator protein-1 (AP-1), a transcription factor that displays antitumor activity. SR 11302 does not activate transcription from the retinoic acid response element (RARE) and also does not display activity at retinoic acid receptors (EC₅₀ > 1 μM for RARα, RARβ, and RARγ).

分子式: C₂₆H₃₂O₂

密度: ~1.0 g/cm³ (Predicted)

分子量: 376.54

熔点: 204.33° C (Predicted)

应用: An inhibitor of activator protein-1

纯度: ≥98%

沸点: ~541.6° C at 760 mmHg (Predicted)

SMILES: CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/C(=O)O)/C)/C2=CC=C(C=C2)C

折射率: n²⁰_D 1.59 (Predicted)

IC50: RARα: EC₅₀50 = > 1 μM ; RARβ: EC₅₀50 = > 1 μM ; RARγ: EC₅₀50 = > 1 μM ; RXRα: EC₅₀50 = > 1 μM

储存/保存方法: Store at -20° C

PK值: pK_a: 4.67 (Predicted)

形态: Solid

可溶性/溶解性: Soluble in DMSO (100 mM), and ethanol (10 mM).

MDL: MFCD09038562

PubChem CID: 9976842

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