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产品描述:

产品名称:N-3-oxo-hexadec-11Z-enoyl-L-Homoserine lactone

CAS号: 479050-91-4

别名: 3-oxo-C16:1-Δ11cis-(L)-HSL; 3- oxo- N- [(3S)- tetrahydro- 2- oxo- 3- furanyl]- (11Z)- hexadecenamide

描述: N-3-oxo-hexadec-11Z-enoyl-L-Homoserine lactone is also known as 3-oxo-C₁₆:1-Δ¹¹cis-(L)-HSL. The N-acylated homoserine lactones (AHLs) comprise one class of autoinducers, each of which generally consists of a fatty acid coupled with homoserine lactone. Regulation of bacterial quorum sensing signaling systems to inhibit pathogenesis represents a new approach to antimicrobial therapy in the treatment of infectious diseases. AHLs vary in acyl group length (C₄-C₁₈), in the substitution of C3 (hydrogen, hydroxyl, or oxo group), and in the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signal specificity through the affinity of transcriptional regulators of the LuxR family. An unspecified positional and geometric isomer of 3-oxo-C₁₆:1-(L)-HSL is produced by the F2/5 strain of A. vitis, the bacterium responsible for grape crown gall and its resulting loss of agricultural productivity.

分子式: C₂₀H₃₃NO₄

分子量: 351.50

应用: An autoinducer

沸点: 84° C

SMILES: CCCCCCC=CCCCCCC(=O)CC(=O)NC1CCOC1=O

折射率: n²⁰_D ~1.49

储存/保存方法: Store at -20° C

形态: Liquid

可溶性/溶解性: Soluble in DMSO (~30 mg/ml), DMF (~30 mg/ml), ethanol, and primary alcohols.

MDL: MFCD11976891

PubChem CID: 53394019

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