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产品描述:

产品名称:Recombinant human PD1 protein, His tagged

英文别名: CD279

描述:

Recombinant human PD1 protein aa1-165 was produced in mammalian cells with C-terminal His tag. The theoretical molecular weight of recombinant PD1 is 17.5 kDa. Purified PD1 protein is near the position of 34 kDa on SDS-PAGE gel under reduced condition.

PD1 protein is purified by proprietary chromatographic techniques.

Entrez Gene summary for PD1:

This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis.

UniProtKB/Swiss-Prot: Q15116 (PD1_HUMAN)

Function: Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen-specific manner. Possible cell death inducer, in association with other factors.

Accession: NP_005009.2

中文别名: PD1蛋白

来源: Mammalian cells

形态: Protein is supplied in 20 mM Tris,150 mM NaCl, 10% Glycerol, pH 7.5

储存/保存方法: Clear solution, frozen.Store at -70°C. At first use, aliquot and store at -70°C to avoid multiple freeze-thaws.

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