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产品描述:

产品名称:Biotinylated Human FGFR1 alpha (IIIc) Protein

背景说明: Fibroblast growth factors (FGFs) comprise a family of at least eighteen structurally related proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differentiation, angiogenesis, wound healing and tumorgenesis. The biological activities of the FGFs are mediated by a family of type I transmembrane tyrosine kinases which undergo dimerization and autophosphorylation after ligand binding.FGFR1 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and correct axial organization during embryonic development, normal skeletogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system.

英文别名: FGF R1a; FGFR1 alpha

Accession: P11362

中文别名: FGFR1 alpha (IIIc) 蛋白

序列: Arg22-Glu374

标签: C-His-Avi

种属: Human

来源: Biotinylated Human FGFR1 alpha (IIIc) Protein is expressed from mammalian with His Tag and Avi Tag at the C-terminal.;It contains Arg22-Glu374.

分子量: The protein has a predicted MW of 42 KDa. Due to glycosylation, the protein migrates to 68-80 KDa based on Bis-TrisPAGE result.

纯度: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

内毒素水平: Less than 1 EU per μg by the LAL method.

形态: Lyophilized from 0.22um filtered solution in PBS (pH 7.4).Normally 5 % trehalose is added as protectant before lyophilization.

储存/保存方法: The product should be stored at -70℃ or -20℃.

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