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产品描述:

产品名称:Recombinant Human TWEAK Receptor/TNFRSF12A

氨基酸序列: EQAPGTAPCS RGSSWSADLD KCMDCASCRA RPHSDFCLGC AAAPPAPFRL LWP

参考文献: 1.Gaudineau B, Fougere M, Guaddachi F, et al. 2012. J Cell Sci, 125: 4475-86.<br/>2.Abend JR, Uldrick T, Ziegelbauer JM. 2010. J Virol, 84: 12139-51.<br/>3.Kang S, Yang C, Luo R. 2008. Biochem Biophys Res Commun, 372: 629-33.<br/>4.Wiley SRandWinkles JA. 2003. Cytokine Growth Factor Rev, 14: 241-9.

Accession: <a href="http://www.uniprot.org/uniprot/Q9NP84" target="_blank">Q9NP84</a>

中文别名: TWEAK Receptor蛋白; TWEAK R蛋白; TNFRSF12A蛋白

Gene IDs: <a href="http://www.ncbi.nlm.nih.gov/gene/51330" target="_blank">51330</a>

种属: Human

来源: Escherichia coli.

纯度: > 95 % by SDS-PAGE and HPLC analyses.

内毒素水平: Less than 1 EU/μg of Recombinant HumanTWEAK Receptor as determined by LAL method.

活性: Fully biologically active when compared to standard. The ED₅₀ as determined by inhibiting TWEAK-dependent proliferation of human umbilical vein endothelial cells (HUVEC) is less than 30 ng/ml, corresponding to a specific activity of > 3.3 × 10⁴ IU/mg, in the presence of 15 ng/ml of Recombinant HumanTWEAK.

形态: Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.

溶解方法: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.

储存/保存方法: This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C. Avoid repeated freeze/thaw cycles.

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