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产品描述:

产品名称:Recombinant Mouse FcRn & B2M Heterodimer (C-6His)

氨基酸序列: SETRPPLMYHLTAVSNPSTGLPSFWATGWLGPQQYLTYNSLRQEADPCGAWMWENQVSWYWEKET TDLKSKEQLFLEALKTLEKILNGTYTLQGLLGCELASDNSSVPTAVFALNGEEFMKFNPRIGNWT GEWPETEIVANLWMKQPDAARKESEFLLNSCPERLLGHLERGRRNLEWKEPPSMRLKARPGNSGS SVLTCAAFSFYPPELKFRFLRNGLASGSGNCSTGPNGDGSFHAWSLLEVKRGDEHHYQCQVEHEG LAQPLTVDLDSSARSSVPVVVDHHHHHH&IQKTPQIQVYSRHPPENGKPNILNCYVTQFHPPHIE IQMLKNGKKIPKVEMSDMSFSKDWSFYILAHTEFTPTETDTYACRVKHASMAEPKTVYWDRDM

背景说明: FcRn complex consist of two subunits: IgG receptor FcRn large subunit p51(alpha chain) and Beta-2-microglobulin(Beta chain). The complexes is similar in structure to MHC class I-like heterodimer. Beta-2-microglobulin involved in the presentation of peptide antigens to the immune system. FcRn binds to the Fc region of monomeric immunoglobulins gamma, mediates the uptake of IgG from milk,Possible role in transfer of immunoglobulin G from mother to fetus. A principal component of antibody transport is the neonatal receptor for the Fc portion of immunoglobulin, a heterodimer of a MHC-1 alpha-chain homolog ( FcRn ) and beta-2-microglobulin ( B2M ).

英文别名: IgG receptor FcRn,Neonatal Fc receptor,FCRN

描述: Recombinant Mouse IgG Fc fragment receptor transporter is produced by our Mammalian expression system and the target gene encoding Ser22-Val301&Ile21-Met119 is expressed with a 6His tag at the C-terminus.

Accession: Q61559&P01887

中文别名: FcRn & B2M Heterodimer蛋白

来源: Human Cells

纯度: Greater than 95% as determined by reducing SDS-PAGE.

内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

形态: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

溶解方法: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

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