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产品描述:

产品名称:Recombinant Mouse IL-36α, 153a.a.

氨基酸序列: RAASPSLRHV QDLSSRVWIL QNNILTAVPR KEQTVPVTIT LLPCQYLDTL ETNRGDPTYM GVQRPMSCLF CTKDGEQPVL QLGEGNIMEM YNKKEPVKAS LFYHKKSGTT STFESAAFPG WFIAVCSKGS CPLILTQELG EIFITDFEMI VVH

参考文献: 1.Nicklin MJ, Barton JL, Nguyen M, et al. 2002. Genomics. 79:718-25.<br/>2.Dinarello C, Arend W, Sims J, et al. 2010. Nat Immunol. 11:973.<br/>3.Barksby HE, Lea SR, Preshaw PM, et al. 2007. Clin Exp Immunol. 149:217-25.<br/>4.Smith DE, Renshaw BR, Ketchem RR, et al. 2000. J Biol Chem. 275:1169-75.<br/>5.Dunn E, Sims JE, Nicklin MJ, et al. 2001. Trends Immunol. 22:533-6.

Accession: <a href="http://www.uniprot.org/uniprot/Q9JLA2" target="_blank">Q9JLA2</a>

中文别名: IL-36α蛋白

Gene IDs: <a href="http://www.ncbi.nlm.nih.gov/gene/54448" target="_blank">54448</a>

种属: Murine

来源: Escherichia coli.

纯度: > 95 % by SDS-PAGE and HPLC analyses.

内毒素水平: Less than 1 EU/μg of rMuIL-36α, 153a.a. as determined by LAL method.

活性: Fully biologically active when compared to standard. The ED₅₀ as determined by inducing IL-6 secretion in murine NIH/3T3 cells is less than 25 ng/ml, corresponding to a specific activity of > 4.0 × 10⁴ IU/mg.

形态: Lyophilized from a 0.2 μm filtered concentrated solution in PBS, 1 mM DTT, 3 % trehalose.

溶解方法: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.

储存/保存方法: This lyophilized preparation is stable at 2-8 °C, but should be kept at - 20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C. Avoid repeated freeze/thaw cycles.

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