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产品描述:

产品名称:Recombinant Human BCMA/TNFRSF17

氨基酸序列: AGQCSQNEYF DSLLHACIPC QLRCSSNTPP LTCQRYCNAS VTNSVKGTNA

参考文献: 1.Kim J, Gross JA, Dillon SR, et al. 2011. Autoimmunity, 44: 69-81.<br/>2.Sun J, Feng J, Li Y, et al. 2006. Biochem Biophys Res Commun, 346: 1158-62.<br/>3.Pelletier M, Thompson JS, Qian F, et al. 2003. J Biol Chem, 278: 33127-33.<br/>4.Laabi Y, Gras MP, Brouet JC, et al. 1994. Nucleic Acids Res, 22: 1147-54.

Accession: <a href="http://www.uniprot.org/uniprot/Q02223" target="_blank">Q02223</a>

中文别名: BCMA蛋白; TNFRSF17蛋白

Gene IDs: <a href="http://www.ncbi.nlm.nih.gov/gene/608" target="_blank">608</a>

种属: Human

来源: Escherichia coli.

纯度: > 98 % by SDS-PAGE and HPLC analyses.

内毒素水平: Less than 1 EU/μg of Recombinant HumanBCMA as determined by LAL method.

活性: Fully biologically active when compared to standard. The ED₅₀ as determined by its ability to inhibit APRIL-mediated proliferation of anti-IgM stimulated murine B cells is no less than 40 ng/ml, corresponding to a specific activity of > 2.5 × 10⁴ IU/mg in the presence of 100 ng/ml human APRIL.

形态: Lyophilized from a 0.2 μm filtered concentrated solution in 30 % acetonitrile, 0.1 % TFA.

溶解方法: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.

储存/保存方法: This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C. Avoid repeated freeze/thaw cycles.

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