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产品描述:

产品名称:Human IL-23 R Protein

背景说明: Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12 . The functional IL-23 receptor complex consists of two receptor subunits, the IL-12 receptor beta 1 subunit (IL-12 R beta 1) and the IL-23-specific receptor subunit (IL-23 R).This receptor associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade.

英文别名: IBD17; IL-23 R; IL-23 receptor; IL23R; IL-23R; interleukin 23 receptor; interleukin-23 receptor

Accession: Q5VWK5-1

中文别名: IL-23 R蛋白

序列: Gly24 - Gly355

标签: C-mFc

种属: Human

来源: Recombinant Human IL-23 R Protein Protein is expressed from mammalian with a mFc at the C-terminal.;It contains Gly24 - Gly355.

分子量: The Protein has a calculated MW of 63.7kDa .As a result of glycosylation, the protein migrates to80-115kDa based on Bis-Tris PAGE.

纯度: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

内毒素水平: Less than 1 EU per μg by the LAL method.

形态: Lyophilized from 0.22um filtered solution in PBS (pH 7.4).Normally 5 % trehalose is added as protectant before lyophilization.

储存/保存方法: The product should be stored at -70℃ or -20℃.

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