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试剂描述:

产品名称:尿酸二氢钠

产品别名:

CAS号:1198-77-2

英文别名:尿酸二氢钠

分子量:190.10

分子式:C₅H₃N₄O₃•Na

纯度:

外观:见爱必信官网

保存方法:Store at -20° C

描述:

Monosodium urate has been reported to be an inflammatory compound. Mechanistic studies suggest that this compound intracellularly engages caspase-1-activating cryopyrin inflammasome, resulting in the production of active IL-1β and IL-18. Experiments have shown that monosodium urate crystals also induce triggering receptor expressed on myeloid cells 1 (TREM-1) expression in infiltrating leukocytes in a murine air-pouch model of crystal-induced acute inflammation. Monosodium urate is also an activator of cryopyrin.

应用:A Cryopyrin inflammatory compound that induces IL-1β production

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