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试剂描述:

产品名称:Pannexin-1 (Panx1), Mimetic Blocking Peptide

产品别名:WRQAAFVDSY

CAS号:

英文别名:Pannexin-1 (Panx1), Mimetic Blocking Peptide

分子量:1242.4

分子式:

纯度: ≥ 95%

外观:见爱必信官网

保存方法:-20°C,2 years

描述:This is a Pannexin-1 (Panx1) mimetic blocking peptide. Pannexin-1 is a recently identified membrane protein that can form gap junction-like connections allowing intercellular passage of dyes when overexpressed in two adjacent oocytes or mammalian epithelial cell lines. Blockade of pannexin-1 in macrophage endogenously expressing the ATP-gated P2X7 receptor (P2X7R) blocks the initial dye uptake, but not the ionic current, and also blocks processing and release of interleukin-1β (IL-1β) in response to P2X7R activation. 

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