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试剂描述:

产品名称:伊比(利亚)蝎毒素

产品别名:

CAS号:129203-60-7

英文别名:伊比(利亚)蝎毒素

分子量:4230.85

分子式:C₁₇₉H₂₇₄N₅₀O₅₅S₇

纯度:≥95%

外观:见爱必信官网

保存方法:Store at -20℃,1 year.

描述:

Iberotoxin is a highly selective and potent blocker of the MaxiK (high conductance Ca²⁺ activated K⁺ channels) that does not affect other types of voltage-dependent K⁺ channels. Because of iberiotoxin's strong ability to block Ca²⁺ activated K⁺ channels, in mammalian motor nerve terminals the compound can induce dihydropyridine sensitive release of ACh. In rat organotypic dorsal striatal slices iberiotoxin and margatoxin were both observed to induce production of c-fos like mRNA and protein. Iberiotoxin is an inhibitor of MaxiKα.

应用:A highly selective and potent high conductance Ca²⁺-activated K⁺ channel blocker

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