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抑制剂描述:

产品名称:Fibronectin Adhesion-promoting Peptide

产品别名:见爱必信官网

英文别名:Fibronectin Adhesion-promoting Peptide

靶点:Others

CAS:125720-21-0

纯度:95%

外观:见爱必信官网

保存方法:Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.

描述:Fibronectin Adhesion-promoting Peptide (Heparin Binding Peptide) is one of the heparin-binding amino acid sequences found in the carboxy-terminal heparin-binding domain of fibronectin. It promotes assembly of mesenchymal stem cell (MSC) spheroids into larger aggregates. Fibronectin Adhesion-promoting Peptide directly promotes the adhesion, spreading, and migration of endothelial cells by reacting with heparin binding domains of cells.

溶解性:H2O : 2 mg/mL (1.95 mM; Need ultrasonic and warming)

体外研究:

GRGDS and Heparin Binding Peptide (WQPPRARI peptide) micropatterns increase the endothelialisation of prosthetic materials in vitro. WQPPRARI peptide also enhances haptotactic cell migration. The anti-apoptotic effects of fibronectin require the presence of the WQPPRARI sequence, which may be due to synergistic survival signals mediated by this sequence and by the RGD motif. RDGS and WQPPRARI peptides promote cell adhesion through different activation pathways that induce different forms of adhesion which can be highlighted through the analysis of focal and fibrillar contacts.

体内研究:

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