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- 品牌：爱必信(absin)
- 产地：中国
- 货号：abs816234
- cas：1609402-14-3
- 价格： ￥1403/瓶
- 发布日期： 2022-04-07
- 更新日期： 2025-09-19
| 产地 | 中国 |
| 品牌 | 爱必信(absin) |
| 货号 | abs816234 |
| 用途 | 见爱必信官网 |
| 英文名称 | 见爱必信官网 |
| 包装规格 | 5mg,5mg,5mg,25mg,25mg,25mg,100mg,100mg,100mg |
| 纯度 | 98%% |
| CAS编号 | 1609402-14-3 |
| 别名 | HA-15 |
| 是否进口 | 否 |
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公告提醒:爱必信所有产品和服务仅用于科学研究,不用于临床应用及其他用途提供产品和服务(也不为任何个人提供产品和服务)!
抑制剂描述: 产品名称:HA15 产品别名:见爱必信官网 英文别名:HA15 靶点:Autophagy;HSP CAS:1609402-14-3 纯度:98% 外观:见爱必信官网 保存方法:Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution. 描述:HA15 is a molecule that targets specifically <b>BiP/GRP78/HSPA5</b>. HA15 displays <b>anti-cancerous</b> activity on all melanoma cells tested, including cells isolated from patients and cells that developed resistance to BRAF inhibitors. 溶解性:DMSO :93 mg/mL (199.32 mM) 体外研究:
HA15 induces ER stress leading to cancer cell death in vitro and overcomes BRAF inhibitor resistance in melanoma cells. 体内研究:HA15 induces ER stress leading to cancer cell death and exhibits strong efficacy in xenograft mouse models with melanoma cells either sensitive or resistant to BRAF inhibitors.
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- 手机：18438616290