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抑制剂描述:

产品名称:HM03

产品别名:见爱必信官网

英文别名:HM03

靶点:

CAS:500565-15-1

纯度:98%

外观:见爱必信官网

保存方法:Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.

描述:HM03 is a potent and selective HSPA5 (Heat shock 70kDa protein 5, also known as Bip, Grp78) inhibitor. HM03 has anticancer activity.

溶解性:DMSO : 125 mg/mL (270.00 mM; Need ultrasonic)

体外研究:

HM03 (0.1-50 μM; 72 hours) exhibits over 50% inhibition at 25 μM concentration in HCT116 cells.
HM03 forms more binding interactions with HSPA5 and HSPA9 than with the other HSP70 proteins.
HM03 exhibits promising inhibition activities from cancer cell viability and tumor inhibition assays.

体内研究:

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