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产地 | 中国 |
品牌 | 爱必信(absin) |
货号 | abs810638 |
用途 | 见爱必信官网 |
英文名称 | 见爱必信官网 |
包装规格 | 5mg,5mg,5mg,5mg,10mg,10mg,10mg,10mg,50mg,50mg,50mg,50mg,100mg,100mg,100mg,100mg |
纯度 | >98%% |
CAS编号 | 1129669-05-1 |
别名 | The GSK3β Inhibitor XIX, IM 12, IM-12,IM12 |
是否进口 | 否 |
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抑制剂描述: 产品名称:IM-12 产品别名:见爱必信官网 英文别名:IM-12 靶点:GSK-3 CAS:1129669-05-1 纯度:>98% 外观:见爱必信官网 保存方法:Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution. 描述: The GSK3β Inhibitor XIX, IM-12 is a selective GSK-3β inhibitor with IC50 of 53 nM, and also enhances canonical Wnt signalling. 溶解性:Ethanol :10 mg/mL (26.49 mM) warmed 体外研究:
In hNPCs, IM-12 inhibits GSK-3β activity with IC50 of 3.8 μM and subsequently increases β-catenin concentration significantly. Through the activation of canonical Wnt signalling pathway, IM-12 promotes the neuronal differentiation of human neural progenitor cells. 体内研究:
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