|
- 英文名称：见爱必信官网
- 品牌：爱必信(absin)
- 产地：中国
- 货号：abs810754
- cas：950455-15-9
- 价格： ￥1151/瓶
- 发布日期： 2022-04-07
- 更新日期： 2025-11-07
| 产地 | 中国 |
| 品牌 | 爱必信(absin) |
| 货号 | abs810754 |
| 用途 | 见爱必信官网 |
| 英文名称 | 见爱必信官网 |
| 包装规格 | 5mg,5mg,5mg,5mg,10mg,10mg,10mg,10mg,50mg,50mg,50mg,50mg,100mg,100mg,100mg,100mg |
| 纯度 | >98%% |
| CAS编号 | 950455-15-9 |
| 别名 | 利普司他丁-1 |
| 分子式 | |
| 是否进口 | 否 |
|
公告提醒:爱必信所有产品和服务仅用于科学研究,不用于临床应用及其他用途提供产品和服务(也不为任何个人提供产品和服务)!
抑制剂描述: 产品名称:Liproxstatin-1 产品别名:见爱必信官网 英文别名:Liproxstatin-1 靶点:Ferroptosis CAS:950455-15-9 纯度:>98% 外观:见爱必信官网 保存方法:Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution. 描述: Liproxstatin-1 is able to suppress ferroptosis in cells, in Gpx4(-/-) mice, and in a pre-clinical model of ischaemia/reperfusion-induced hepatic damage. 溶解性:
DMSO : 63 mg/mL (184.8 mM) 体外研究:
Liproxstatin-1 is able to inhibit ferroptosis in the low nanomolar range and inhibit the growth of Gpx4?/?cells with IC50 of 22 nM. Liproxstatin-1 (50 nM) completely prevents lipid peroxidation in Gpx4?/?cells. Liproxstatin-1 (200 nM) protects against FINs, such as BSO (10 μM), erastin (1 μM) and RSL3 (0.5 μM), in a dose dependent manner, whereas it fails to rescue cell death induced by staurosporine (0.2 μM) and H2O2 (200 μM). 体内研究:Liproxstatin-1 remarkably extends survival compared with the vehicle-treated group, delays ferroptosis in tubular cells, and mitigates tissue injury in ischaemia/reperfusion-induced liver injury.
产品信息订购:
|
- 手机：18438616290