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抑制剂描述:

产品名称:L-Quisqualic acid

产品别名:见爱必信官网

英文别名:L-Quisqualic acid

靶点:AMPAR

CAS:52809-07-1

纯度:≥98%

外观:见爱必信官网

保存方法:Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.

描述:

L-Quisqualic acid acts as an agonist for mGluR-1 (metabotropic glutamate receptor 1), and can be used to differentiate between mGluR-1 and mGluR-4. It has been reported to induce a slow K(+)-current response in B6 neurons of Aplysia buccal ganglia. It has been shown to inhibit human PSM (glutamate carboxypeptidase II, GCPII), an enzyme of the central nervous system and the human prostate, and may thus provide neuroprotection and could be useful for the imaging, detection, and treatment of prostate cancer. It has also been shown to increase the release of acetylcholine from the rat hippocampus and striatum. L-Quisqualic acid is an activator of GluR.

溶解性:Soluble in ethanol (<0.17 mg/mL), water (0.5 mg/mL), 0.1 M HCl (1.4 mg/mL), 1 M NH4OH (20 mg/mL), 10% Ammonium hydroxide (0.5 mg/mL), and 1eq. NaOH (100 mM). Insoluble in organic solvents.

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