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抑制剂描述:

产品名称:Nogo-66 (1-40)

产品别名:见爱必信官网

英文别名:Nogo-66 (1-40)

靶点:Others

CAS:475221-20-6

纯度:84%

外观:见爱必信官网

保存方法:Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.

描述:

Peptide fragment corresponding to residues 1 - 40 of Nogo-66, the domain of the myelin protein Nogo that inhibits axonal outgrowth. Acts as a competitive antagonist at the Nogo-66 receptor (NgR); blocks Nogo-66- and CNS myelin-induced inhibition of axonal growth, but does not reduce myelin-associated glycoprotein (MAG) inhibition of neurite outgrowth in vitro. Promotes regeneration of hemisected spinal axons and locomotor recovery following spinal injury in vivo.

溶解性:Soluble to 1 mg/ml in water

体外研究:

体内研究:

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