公告提醒:爱必信所有产品和服务仅用于科学研究,不用于临床应用及其他用途提供产品和服务(也不为任何个人提供产品和服务)!

抑制剂描述:

产品名称:Palmitic Acid

产品别名:见爱必信官网

英文别名:Palmitic Acid

靶点:Miscellaneous

CAS:57-10-3

纯度:>98%

外观:见爱必信官网

保存方法:Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.

描述:

Palmitic acid is the most common saturated fatty acid found in animals, plants and microorganisms with anti-tumor activity.

溶解性:DMSO :51 mg/mL (198.89 mM)

体外研究:

Palmitic acid (PA) binds TLR4 via the adaptor protein MD2 and that the TLR4 signal induced by PA stimulates dendritic cells activation and maturation accompanied by a robust IL-1β response. Palmitic acid is a TLR4/MD-2 ligand. It exerts pro-inflammatory activity through TLR4.

体内研究:In a dose-dependent fashion, palmitic acid rapidly reduces mouse locomotor activity by a mechanism that did not rely on TLR4, MyD88, IL-1, IL-6 or TNFα but is dependent on fatty acid chain length. Palmitic acid induces anxiety-like behavior in mice while increasing amygdala-based serotonin metabolism.

产品信息订购:

产品更多信息请进入爱必信网站咨询