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- 品牌：爱必信(absin)
- 产地：中国
- 货号：abs810572
- cas：1011557-82-6
- 价格： ￥2211/瓶
- 发布日期： 2022-04-07
- 更新日期： 2025-09-18
| 产地 | 中国 |
| 品牌 | 爱必信(absin) |
| 货号 | abs810572 |
| 用途 | 见爱必信官网 |
| 英文名称 | 见爱必信官网 |
| 包装规格 | 5mg,5mg,5mg,5mg,10mg,10mg,10mg,10mg,50mg,50mg,50mg,50mg,100mg,100mg,100mg,100mg |
| 纯度 | 98%% |
| CAS编号 | 1011557-82-6 |
| 别名 | Tenovin 6; Tenovin6 |
| 是否进口 | 否 |
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抑制剂描述: 产品名称:Tenovin-6 产品别名:见爱必信官网 英文别名:Tenovin-6 靶点:Sirtuin CAS:1011557-82-6 纯度:98% 外观:见爱必信官网 保存方法:Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution. 描述: Tenovin-6 is the water soluble analog of Tenovin-1 and acts as a potent SIRT1 (IC50=21 uM) and SIRT2 (IC50= 10 uM) inhibitor as well as p53 activator. 溶解性:DMSO :98 mg/mL (215.55 mM) 体外研究:
Tenovin-6 is a more water-soluble analog of tenovin-1. Tenovin-6 acts through inhibition of the protein-deacetylating activities of SirT1 and SirT2. Tenovin-6 inhibits the protein deacetylase activities of purified human SIRT1, SIRT2, and SIRT3 in vitro with IC50 of 21 μM, 10 μM, and 67 μM, respectively. 体内研究:Tenovin-6 (50 mg/kg, i.p.) inhibits the growth of tumor in mice.
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