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- 品牌：爱必信(absin)
- 产地：中国
- 货号：abs812936
- cas：1314890-29-3
- 价格： ￥811/瓶
- 发布日期： 2022-04-07
- 更新日期： 2025-09-19
| 产地 | 中国 |
| 品牌 | 爱必信(absin) |
| 货号 | abs812936 |
| 用途 | 见爱必信官网 |
| 英文名称 | 见爱必信官网 |
| 包装规格 | 2mg,2mg,2mg,2mg,5mg,5mg,5mg,5mg,10mg,10mg,10mg,10mg,25mg,25mg,25mg,25mg |
| 纯度 | 98%% |
| CAS编号 | 1314890-29-3 |
| 是否进口 | 否 |
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抑制剂描述: 产品名称:TMP269 产品别名:见爱必信官网 英文别名:TMP269 靶点:HDAC CAS:1314890-29-3 纯度:98% 外观:见爱必信官网 保存方法:Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution. 描述: TMP269 is a potent, selective class IIa HDAC inhibitor with IC50 of 157 nM, 97 nM, 43 nM and 23 nM for HDAC4, HDAC5, HDAC7 and HDAC9, respectively. 溶解性:Ethanol :2mg/mLwarmed(3.88mM) 体外研究:
TMP269 has no impact on the mitochondrial activity and/or the viability of human CD4+ T cells at 10 μM, and may be used as tools to identify the endogenous substrates of the class IIa HDAC enzymes. In IEC-18 intestinal epithelial cells, TMP269 prevents cell cycle progression, DNA synthesis, and proliferation induced in response to G protein-coupled receptor/PKD1 activation. 体内研究:
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