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- 品牌：爱必信(absin)
- 产地：中国
- 货号：abs810003
- cas：109511-58-2
- 价格： ￥441/瓶
- 发布日期： 2022-04-07
- 更新日期： 2025-09-18
| 产地 | 中国 |
| 品牌 | 爱必信(absin) |
| 货号 | abs810003 |
| 用途 | 见爱必信官网 |
| 英文名称 | 见爱必信官网 |
| 包装规格 | 5mg,5mg,5mg,10mg,10mg,10mg,25mg,25mg,25mg,50mg,50mg,50mg,100mg,100mg,100mg |
| 纯度 | >98%% |
| CAS编号 | 109511-58-2 |
| 别名 | U0126;U 0126 |
| 是否进口 | 否 |
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公告提醒:爱必信所有产品和服务仅用于科学研究,不用于临床应用及其他用途提供产品和服务(也不为任何个人提供产品和服务)!
抑制剂描述: 产品名称:U0126 产品别名:见爱必信官网 英文别名:U0126 靶点:MEK CAS:109511-58-2 纯度:>98% 外观:见爱必信官网 保存方法:Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution. 描述: U-0126 is a selective MAP Kinase Kinase inhibitor, displaying a preference for MEK-1 (IC50 = 72 nM) and MEK-2 (IC50 58nM). It is known that U-0126 binds to MEK in a noncompetitive manner compared to ATP. Studies suggest that U-0126 antagonizes the transcription of AP-1, via the inhibition of MEK. In addition, U-0126 has been observed to inhibit promoters containing an AP-1 response element, while in contrast having no effect on promoters that lack an AP-1 response group. U-0126 is also useful in neuronal studies in mice since it displays inhibitory effects against oxidative stress. U-0126 is an activator of PGC-1, mtTFA and nuclear respiratory factor. 溶解性:Soluble in DMSO at 200 mg/mL 体外研究: 体内研究:
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- 手机：18438616290