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抑制剂描述:

产品名称:WM-8014

产品别名:见爱必信官网

英文别名:WM-8014

靶点:Histone Acetyltransferase

CAS:2055397-18-5

纯度:≥98%

外观:见爱必信官网

保存方法:Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.

描述:

WM-8014 is an inhibitor of MOZ, a member of histone acetyltransferases, with an IC50 of 55 nM.

溶解性:DMSO : ≥ 250 mg/mL (650.33 mM)

体外研究:

WM-8014 (Compound 36) is an inhibitor of MOZ, with an IC50 of 55 nM. WM-8014 causes cell senescence and suppresses the proliferation with IC50s of 1.6 μM and 551 nM, respectively. WM-8014 also reduces mRNA coding for the MOZ gene Cdc6 by 65.1%.

体内研究:

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