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产品名称:Wnt agonist 1

产品别名:见爱必信官网

英文别名:Wnt agonist 1

靶点:Wnt

CAS:853220-52-7

纯度:≥98%

外观:见爱必信官网

保存方法:Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.

描述:

Wnt Agonist is a cell-permeable pyrimidine compound that acts as, at an IC₅₀ > 60 μM, a potent and selective activator of Wnt signaling. In addition to mimicking the effect of Wnt, Wnt Agonist has also induced β-catenin and T-cell fate-dependent transcriptional activity in HEK-293T cells at an EC₅₀ = 700 nM. When applied to Xenopous embryos Wnt Agonist caused substantial head defects development. Wnt Agonist has also been observed to enhance beta cell expansion in vitro. The compound is beneficial for studying the effects of Wnt pathway due to the activation of Wnt without inhibiting the activity of GSK-3β.

溶解性:Soluble in DMSO (10 mg/ml), ethanol (5 mg/ml), and 100% ethanol (25 mg/ml).

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