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- 品牌：爱必信(absin)
- 产地：中国
- 货号：abs811894
- cas：7481-89-2
- 价格： ￥725/瓶
- 发布日期： 2022-04-07
- 更新日期： 2025-09-18
| 产地 | 中国 |
| 品牌 | 爱必信(absin) |
| 货号 | abs811894 |
| 用途 | 见爱必信官网 |
| 英文名称 | 见爱必信官网 |
| 包装规格 | 100mg,100mg,200mg,200mg |
| 纯度 | ≥98%% |
| CAS编号 | 7481-89-2 |
| 别名 | 扎西他滨;2',3'-二脱氧胞苷;双去氧胞嘧啶核酸 |
| 是否进口 | 否 |
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抑制剂描述: 产品名称:Zalcitabine 产品别名:见爱必信官网 英文别名:Zalcitabine 靶点:Reverse Transcriptase CAS:7481-89-2 纯度:≥98% 外观:见爱必信官网 保存方法:Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution. 描述: 溶解性:DMSO : 62.5 mg/mL (295.90 mM; Need ultrasonic) 体外研究:
Zalcitabine is a dideoxynucleoside antiretroviral agent that is phosphorylated to the active metabolite 2',3'-dideoxycytidine 5'-triphosphate (ddCTP) within both uninfected and HIV-infected cells. At therapeutic concentrations, ddCTP inhibits HIV replication by inhibiting the enzyme reverse transcriptase and terminating elongation of the proviral DNA chain. Zalcitabine exhibits the inhibition effect on the cellular uptake of [3H]-PAH in CHO/hOAT1 cells with an IC50 value of 1.23 mM. Furthermore, the cellular uptake of zalcitabine increased threefold with the enhancement of hOATI activity in CHO/hOAT1 cells. 体内研究:
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