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- 品牌：爱必信(absin)
- 产地：中国
- 型号：50mg,50mg,50mg,100mg,100mg,100mg,200mg,200mg,200mg,500mg,500mg,500mg
- 货号：abs816185
- cas：62717-42-4
- 价格： ￥835/瓶
- 发布日期： 2022-04-07
- 更新日期： 2025-09-18
| 产地 | 中国 |
| 品牌 | 爱必信(absin) |
| 货号 | abs816185 |
| 用途 | 见爱必信官网 |
| 英文名称 | 见爱必信官网 |
| 包装规格 | 50mg,50mg,50mg,100mg,100mg,100mg,200mg,200mg,200mg,500mg,500mg,500mg |
| 纯度 | 98%% |
| CAS编号 | 62717-42-4 |
| 别名 | SKF 38393 hydrochloride;(±)-SKF-38393 hydrochloride;SKF-38393A |
| 是否进口 | 否 |
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抑制剂描述: 产品名称:SKF38393 HCl 产品别名:见爱必信 英文别名:SKF38393 HCl 靶点:Dopamine Receptor CAS:62717-42-4
纯度:98% 外观:见爱必信 保存方法:Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution. 描述: SKF38393 HCl is a selective dopamine D1/D5 receptor agonist.
溶解性:DMSO : 54 mg/mL (185.1 mM) 体外研究: SKF38393 (50-100 μM) induces long-lasting synaptic potentiation in a protein synthesis-dependent manner. In rat prefrontal cortical neurons in vitro, SKF 38393 mimicks the effects of DA on I(NaP), and modulates a persistent sodium current. In the auditory cortex, SKF38393 affects long-term memory formation and consolidation by activating the downstream effectors adenylyl cyclase and phospholipase C-prominent proteomic alterations.
体内研究:SKF 38393(6 mg/kg, i.p.) prevents the scopolamine-induced impairment of performance of a T-maze working memory task. In male NMRI mice, SKF38393 (1 μg/mouse) impaires context-dependent fear learning.
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