公告提醒:爱必信所有产品和服务仅用于科学研究,不用于临床应用及其他用途提供产品和服务(也不为任何个人提供产品和服务)!

抑制剂描述:

产品名称:TLCK hydrochloride

产品别名:见爱必信官网

英文别名:TLCK hydrochloride

靶点:Others

CAS:4238-41-9;4272-74-6

纯度:≥95%

外观:见爱必信官网

保存方法:Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.

描述:

TLCK hydrochloride (TLCK) is an active site-directed agent that irreversibly inhibits trypsin-like serine proteases such as granzyme D and tryptase. Cysteine proteases and other enzymes may be inhibited by TLCK through non-selectively interactions with thiol groups. To prevent proteolytic degradation, TLCK may be employed in protein purification protocols. TLCK has been shown to selectively inactivate clostripain obtained from C. histolyticum. Also, TLCK has been observed to inhibit other proteases including plasminogen (plasmin), thrombin, papain and some kinases including PKC. The compound has demonstrated Inhibition of LPS-induced expression of COX-2 in macrophages. TLCK hydrochloride is an inhibitor of trypsin.

溶解性:Soluble in water (700 mg/L at 25 °C), chloroform (44.51 g/100mL at 25 °C), dichloromethane (19.20 g/100mL at 25 °C), methanol (9.98 g/100mL at 25 °C), DMSO (50 mM), ethanol (1.28 g/100mL at 25 °C)

体外研究:

体内研究:

产品信息订购:

产品更多信息请进入爱必信网站咨询