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抑制剂描述:

产品名称:NF-kB Inhibitor, SN50

产品别名:见爱必信官网

英文别名:NF-kB Inhibitor, SN50

靶点:NF-kB

CAS:213546-53-3

纯度: ≥ 95%

外观:见爱必信官网

保存方法:Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.

描述:

This is a membrane-translocating peptide sequence consisting of the hydrophobic region of the signal peptide of Kaposi fibroblast growth factor (K-FGF) attached to a NF-kB nuclear localization sequence (NLS). SN50 inhibits translocation of the NF-kB activ

溶解性:

体外研究:

体内研究:Treatment with SN50 accelerates the recovery of motor functional outcome from 1st to 4th day. Animals subjected to SN50 pretreatment demonstrate a significant decrease in the visuospatial learning latencies relative to the control group at 7 and 8 days post-TBI. Pretreatment with SN50 results in a significant reduction of NF-κB p65 protein levels from 6 to 48 h post-TBI and TNF-a protein levels from 12 to 48 h post-TBI.

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