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抑制剂描述:

产品名称:AS-8351

产品别名:见爱必信官网

英文别名:AS-8351

靶点:Histone Demethylase

CAS:796-42-9

纯度:>98%

外观:见爱必信官网

保存方法:Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.

描述:

AS 8351 induces reprogramming of human fetal lung fibroblasts into functional cardiomyocytes, in combination with CHIR 99021, A83-01, BIX 01294, SC1, Y-27632, OAC2, SU 16f and JNJ 10198409.

溶解性:

体外研究:

AS8351 affects epigenetic modifications by competing with α-ketoglutarate (α-KG) for chelating iron in certain epigenetic enzymes, such as the JmjC domain-containing histone demethylases (JmjC-KDMs) that require α-KG and iron as co-factors.

体内研究:

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