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- 品牌：爱必信(absin)
- 产地：中国
- 货号：abs817423
- cas：57-71-6
- 价格： ￥431/瓶
- 发布日期： 2022-04-07
- 更新日期： 2025-07-20
| 产地 | 中国 |
| 品牌 | 爱必信(absin) |
| 货号 | abs817423 |
| 用途 | 见爱必信官网 |
| 英文名称 | 见爱必信官网 |
| 包装规格 | 25mg,25mg,25mg,25mg,50mg,50mg,50mg,50mg,100mg,100mg,100mg,100mg,200mg,200mg,200mg,200mg |
| 纯度 | >99%% |
| CAS编号 | 57-71-6 |
| 别名 | 2,3-丁烷二酮一肟;二乙酰一肟;NSC 660;NSC 116103 |
| 是否进口 | 否 |
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公告提醒:爱必信所有产品和服务仅用于科学研究,不用于临床应用及其他用途提供产品和服务(也不为任何个人提供产品和服务)!
抑制剂描述: 产品名称:2,3-Butanedione 2-Monoxime 产品别名:见爱必信官网 英文别名:2,3-Butanedione 2-Monoxime 靶点:ATPase CAS:57-71-6 纯度:>99% 外观:见爱必信官网 保存方法:Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution. 描述: 溶解性:10 mM in DMSO 体外研究:
BDM inhibits skeletal muscle myosin-II, but it does not inhibit the ATPase activity of the other myosins. BDM has a broad effect on many non-myosin proteins (many uncharacterized), and thus should not be used in whole-cell experiments as a myosin inhibitor. BDM inhibits the L-type Ca2+-channel and reduces the opening probability, thereby increasing the closed time of this particular channel. BDM drives nonspecific protein dephosphorylation of many cellular proteins, including ion channels. 体内研究:BDM significant lowers the blood pressure in normo- and hypertensive rats. BDM has been shown to improve right atrial function in a porcine model of allogenic heart transplantation.
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