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试剂描述:

产品名称:灭瘟素S盐酸盐

产品别名:

CAS号:3513-03-9

英文别名:灭瘟素S盐酸盐

分子量:458.9

分子式:C₁₇H₂₆N₈O₅•HCl

纯度:95%

外观:见爱必信官网

保存方法:Store at -20°C,2 years.

描述:

Blasticidin S Hydrochloride, like puromycin , belongs to a group of cytosine amino nucleoside antibiotics. Blasticidin S is isolated from Streptomyces griseochromogenes and inhibits protein synthesis in both prokaryotic and eukaryotic cells, it acts quickly by inhibiting peptide bond formation by the ribosome.

The blasticidin S resistance gene (BSR), found in Bacillus cereus K55-S1, has been used in multiple studies for its use as a selective compound. Resistance is conferred by expression of one of two Blasticidin S deaminase genes: BSD from Aspergillus terreus or bsr from Bacillus cereus. These deaminases convert Blasticidin S to a nontoxic deaminohydroxy derivative.

应用:An antibiotic inhibiting protein synthesis

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